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Current best evidence on prescribed drugs

Current best evidence on prescribed drugs

H

J

Janssen COVID-19 Vaccine

K

Q

S

Sacituzumab govitecan

Sacubitril/valsartan

Sebelipase alfa

Segesterone acetate and ethinyl estradiol vaginal system

Serdexmethylphenidate and dexmethylphenidate

Sodium phenylbutyrate and taurursodiol

Sodium zirconium cyclosilicate

Sofosbuvir and velpatasvir

Sofosbuvir, velpatasvir and voxilaprevir

Spikevax (Moderna COVID-19 Vaccine)

Striverdi Respimat

Sulfur hexafluoride lipid microsphere

T

Tafamidis meglumine

Tafluprost ophthalmic solution

Taliglucerase alfa

Technetium Tc 99m tilmanocept

Tedizolid phosphate

Telotristat ethyl

Tezacaftor and ivacaftor

Tisotumab vedotin

Triclabendazole

Trifluridine and tipiracil

Tudorza Pressair

U

Umeclidinium and vilanterol

Uridine triacetate

W

X

Y

Z

Ziv-aflibercept

B

B-cell maturation antigen-directed CD3 T-cell engagers

B-lymphocyte stimulator-specific inhibitors

BCL-2 inhibitors

Benzodiazepines

Beta-3 adrenergic agonists

Bispecific gp100 peptide-HLA-directed CD3 T cell engagers

Bradykinin B2 receptor antagonists

C

C type natriuretic peptide analogs

CC chemokine receptor type 4 (CCR4)- directed monoclonal antibodies

CD123-directed cytotoxins

CD19-directed CD3 T-cell engagers

CD19-directed cytolytic antibodies

CD20-directed CD3 T-cell engagers

CD20-directed cytolytic antibodies

CD22-directed antibody drug conjugates

CD22-directed cytotoxins

CD3-directed antibody

CD30-directed anitbody-drug conjugates

CD38-directed cytolytic antibodies

CD4-directed post-attachment HIV-1 inhibitors

CD79b-directed antibody-drug conjugate

CFTR Potentiators

CMV DNA terminase complex inhibitors

CTFR potentiators

CYP17 inhibitors

Calcineurin-inhibitor immunosuppressants

Calcitonin gene-related peptide antagonists

Calcitonin gene-related peptide receptor antagonists

Calcitonin-gene related peptide antagonists

Calcium-sensing receptor agonists

Carboxypeptidase

Cardiac myosin inhibitors

Catechol-O-methyltransferase inhibitors

Central alpha-2 adrenergic agonists

Central nervous system stimulants

Cephalosporin antibacterials

Combination hormonal contraceptives

Complement 5a receptor antagonists

Complement inhibitors

Corticosteroids

Cortisol synthesis inhibitors

Cyclic pyranopterin monophosphate

Cystic fibrosis transmembrane conductance regulator (CFTR) potentiators

Cystic fibrosis transmembrane conductance regulator potentiators

Cytolytic agents

Cytomegalovirus pUL97 kinase inhibitors

Cytotoxic T-lymphocyte antigen 4 blocking antibodies

Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) blocking antibodies

D

Deacetylase inhibitors

Diarylquinoline antimycobacterials

Dipeptidyl peptidase-4 (DPP-4) inhibitors

Dipeptidyl peptidase-4 inhibitors

Disclosing agents

Dopamine-2 antagonists

E

Endothelin receptor antagonists (ERA)

Erythroid maturation agents

F

Factor Xa inhibitors

Farnesoid X receptor agonists

Farnesyltransferase inhibitors

Fibroblast growth factor blocking antibodies

Fluoroquinolone antibacterials

G

GD2-binding monoclonal antibodies

Gadolinium-based contrast agent

Gadolinium-based contrast agents

Glucagon-like peptide 1 (GLP-1) receptor agonists

Glucagon-like peptide-1 (GLP-1) receptor agonists

Glucagon-like peptide-2 analogs

Glucosylceramide synthase inhibitors

Gonadotropin-releasing hormone (GnRH) receptor antagonists

Gonadotropin-releasing hormone receptor antagonists

Growth hormone secretagogue receptor agonists

Guanylate cyclase-C agonists

H

HAO1-directed small interfering ribonucleic acid

HER2/neu receptor antagonist

HIV-1 integrase strand transfer inhibitor (INSTI)

Hedgehog pathway inhibitors

Hemoglobin S polymerization inhibitors

Hepatitis C virus (HCV) nucleotide analog NS5B polymerase inhibitors

Histamine-3 receptor antagonists

Human growth hormone analogs

Human growth hormones

Human immunodeficiency virus type 1 (HIV-1) capsid inhibitors

Human immunodeficiency virus type 1 (HIV-1) specific, nonnucleoside reverse transcriptase inhibitor (NNRTI)

Human immunodeficiency virus type 1 gp120-directed attachment inhibitors

Human interleukin-17 receptor A (IL-17RA) antagonists

Human interleukin-17A antagonists

Human monoclonal antibody that binds to Clostridium difficile toxin B

Human parathyroid hormone related peptide analogs

Human vascular endothelial growth factor 2 (VEGF2) antagonist

Human vascular endothelial growth factor inhibitors

Humanized interleukin-17A antagonists

Humanized monoclonal antibody fragment (Fab)

Hydrolytic lysosomal N-terminal tripeptidyl peptidases

Hydrolytic lysosomal glucocerebroside-specific enzymes

Hydrolytic lysosomal glycogen-specific enzyme

Hydrolytic lysosomal glycosaminoglycan (GAG)-specific enzymes

Hydrolytic lysosomal sphingomyelin-specific enzyme

Hyperpolarization-activated cyclic nucleotide-gated channel blockers

Hyperpolarized contrast agents

Hypoxia-inducible factor inhibitors

J

Janus kinase inhibitors

K

Kappa opioid receptor agonists

Kinase Inhibitors

Kinase inhibitors

L

Leukocyte growth factors

Lipoglycopeptide antibacterials

Long-acting beta2-adrenergic agonist (LABA)

Long-acting human insulin analogs

lymphocyte function-associated antigen-1 (LFA-1) antagonists

M

Macrolide antibacterials

Medium-chain triglycerides

Melanocortin 1 receptor (MC1-R) agonists

Melanocortin 4 receptor agonists

Melanocortin receptor agonists

Melatonin receptor agonist

Methyltransferase inhibitors

Microsomal triglyceride transfer protein inhibitors

Microtubule inhibitors

Monoamine oxidase type B (MAO-B) inhibitors

Monoclonal antibodies

Monoclonal antibodies directed against the protective antigen of Bacillus anthracis

mu-opioid receptor agonists

N

Nectin-4-directed antibody and microtubule inhibitor conjugate

Neonatal Fc receptor blockers

Neuroactive steroid gamma-aminobutyric acid A receptor positive modulators

Nitrofuran antiprotozoals

Nitroimidazole antimicrobial

Nitroimidazole antimicrobials

Non-competitive AMPA glutamate receptor antagonists

Non-nucleoside reverse transcriptase inhibitors

Non-steroidal mineralocorticoid receptor antagonists

Nuclear export inhibitors

O

Opioid agonists

Opioid antagonist

Opioid antagonists

Optical imaging agents

Orexin receptor antagonists

Orthopoxvirus VP37 envelope wrapping protein inhibitors

Osmotic laxatives

Oxaborole antifungals

Oxazolidinone antibacterials

P

P2Y12 platelet inhibitors

PCSK9 (proprotein convertase subtilisin kexin type 9) inhibitors

Phenylalanine (Phe)-metabolizing enzymes

Phosphodiesterase 4 (PDE4) inhibitors

Phosphodiesterase 4 inhibitors

Phosphodiesterase 5 inhibitors

Plasma kallikrein inhibitor (monoclonal antibody)

Plasma kallikrein inhibitors

Pleuromutilin antibacterials

Poly (ADP-ribose) polymerase (PARP) inhibitors

Potassium binders

Potassium channel blockers

Programmed death ligand-1 blocking antibodies

Programmed death receptor-1 (PD-1)-blocking antibodies

Programmed death receptor-1 blocking antibodies

Programmed death receptor-1-blocking antibodies

Programmed death-ligand 1 (PD-L1) blocking antibodies

Programmed death-ligand 1 blocking antibodies

Prostacyclin receptor agonists

Prostaglandin analogs

Protease-activated receptor-1 (PAR-1) antagonists

Proteasome inhibitors

Proteolytic enzymes

Pruvate kinase activators

Pyrimidine analogs

Pyrimidine synthesis inhibitors

Q

Quinolone antimicrobials

R

RAS GTPase family inhibitors

RAS GTPase inhibitors

Radioactive diagnostic agents

Radiolabeled somatostatin analogs

Radioligand therapeutic agents

Recombinant adenosine deaminase

Recombinant human lysosomal beta glucuronidases

Recombinant human nerve growth factors

Relatively selective prostaglandin E2 receptor agonists

Rho Kinase inhibitors

Rifamycin antibacterials

S

SLAMF7-directed immunostimulatory antibodies

Sclerostin inhibitors

Selectin blockers

Selective T-cell costimulation blockers

Selective norepinephrine reuptake inhibitors

Selective phosphodiesterase 4 inhibitors

Serotonin 1F receptor agonists

Serotonin-4 receptor agonists

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleotide analogs

Small interfering RNA directed to proprotein convertase subtilisin kexin type 9 mRNA

Sodium glucose co-transporter 2 (SGLT2) inhibitors

Sodium-glucose co-transporter 2 inhibitors

Sodium-glucose cotransporter 2 (SGLT2) inhibitors

Sodium/hydrogen exchanger 3 inhibitors

Soluble Guanylate Cyclase Stimulators

Soluble guanylate cyclase stimulators

Somatostatin analogs

Sphingosine 1-phosphate receptor modulators

Substance P/neurokinin 1 (NK1) receptor antagonists

Survival motor neuron-2 (SMN2)-directed antisense oligonucleotides

Survival of motor neuron 2 splicing modifiers

T

Tetracycline class antibacterials

Thrombopoietin receptor agonists

Thymic stromal lymphopoietin blockers

Tissue nonspecific alkaline phosphatase

Transthyretin stabilizers

Transthyretin-directed antisense oligonucleotides

Transthyretin-directed small interfering RNA

Triterpenoid antifungals

Trop-2-directed antibody and topoisomerase inhibitor conjugate

Tryptophan hydroxylase inhibitors

Type I interferon receptor antagonists

Tyrosine kinase 2 (TYK2) inhibitors

U

Ultrasound contrast agents

Unknown mechanism of action

V

Vascular endothelial growth factor (VEGF) inhibitors

Vascular endothelial growth factor inhibitors

Vasoconstrictors

Vasopressin receptor agonists

Vesicular monoamine transporter 2 inhibitors

Von Willebrand factor-directed antibody fragment

Z

Zaire ebolavirus glycoprotein directed human monoclonal antibodies

B

C

D

G

M

Musculoskeletal

N

R

S

V

Other

B

BTG International

BioCryst Pharmaceuticals

BioDelivery Sciences International, Inc.

Biohaven Pharmaceuticals

Blue Earth Diagnostics

Blueprint Medicines

Boehringer Ingelheim

Bracco Diagnostics

Braintree Laboratories

Bristol Myers Squibb

Bristol-Myers Squibb

C

Cara Therapeutics

Cardinal Health

Catalyst Pharmaceuticals

Celgene Corporation

Clovis Oncology

D

Deciphera Pharmaceuticals

Dermavant Sciences

Dutch Ophthalmic

E

Eiger Biopharmaceuticals

Eli Lilly and Company

Elusys Therapeutics

Emergent BioSolutions

F

G

G1 Therapeutics

GalaxoSmithKline

Genzyme Corporation

Gilead Sciences

GlaxoSmithKline

Global Blood Therapeutics

Greenwich Biosciences

H

Harmony Biosciences

Horizon Therapeutics

I

Idorsia Pharmaceuticals

Intercept Pharmaceuticals

Intra-Cellular Therapies

J

Janssen Biotech

Janssen Pharmaceuticals

Janssen Products

Jazz Pharmaceuticals

K

Kadmon Pharmaceuticals

Karyopharm Therapeutics

Kythera Biopharms

L

La Jolla Pharma

Life Molecular Imaging

Lupin Pharmaceuticals

M

Mallinckrodt Hospital Products

Marinus Pharmaceuticals

Melinta Therapeutics

Metuchen Pharmaceuticals

Mirati Therapeutics

Mirum Pharmaceuticals

Mitsubishi Tanabe Pharma

Mycovia Pharmaceuticals

Mylan Ireland Ltd

Myovant Sciences

N

Nabriva Therapeutics

Neurocrine Biosciences

O

On Target Laboratories

Origin Biosciences

Otsuka Pharmaceutical

P

PTC Therapeutics

Palatin Technologies

Paratek Pharmaceuticals

Pfizer-BioNTech

Phathom Pharmaceuticals

Progenics Pharmaceuticals

Puma Biotechnology

Q

QED Therapeutics

R

Recordati Rare Disease

Recordati Rare Diseases

RedHill Biopharma

Regeneron Pharmaceuticals

Revance Therapeutics

Rhythm Pharmaceuticals

Ridgeback Biotherapeutics

Rigel Pharmaceuticals

T

TG Therapeutics

TaiMed Biologics

TerSera Therapeutics

Tetraphase Pharmaceuticals

Teva Pharmaceuticals

Teva Respiratory

The Feinstein Institutes for Medical Research

Travere Therapeutics

U

UCLA Nuclear Medicine

UIHC PET Imaging

United Therapeutics

Urovant Sciences

V

Vanda Pharmaceuticals

Vericel Corporation

Vertex Pharmaceuticals

ViiV Healthcare

W

Wellstat Therapeutics

X

Xspire Pharmaceuticals

Y

Y-mAbs Therapeutics

Z

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OFFERING OUR SUPPORT DURING COVID-19
As part of our response to the ongoing COVID-19 global epidemic, we are temporarily making DRUGDOCS^®open access in order to support medical professionals, researchers, policy makers, and others who are working to address this health crisis.

WHY DRUGDOCS^®?
DRUGDOCS^®provides current best evidence on prescribed drugs. This information has been collected by Thera-Business Consulting using an independent, comprehensive and non-biased literature search strategy. Documents included in the DRUGDOCS^®database are in no way influenced by third party sponsorship.

FDA Medwatch News Feed

Jarman’s Midwest Cleaning Systems, Inc. Issues Voluntary Nationwide Recall of Alcohol Antiseptic 80% Topical Solution Hand Sanitizer Non-sterile Solution and Isopropyl Alcohol Antiseptic 75% Topical Solution Hand Sanitizer Non-sterile Solution Due to Presence of Methanol | Tue, 28 Mar 2023 00:00:00 EDT

Canton, SD, Jarman’s Midwest Cleaning Systems, Inc. is voluntarily recalling all lots of Alcohol Antiseptic 80% Topical Solution Hand Sanitizer Non-sterile Solution and Isopropyl Alcohol Antiseptic 75% Topical Solution Hand Sanitizer Non-sterile Solution to the consumer level. FDA testing found the ...

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Risks with Exactech Joint Replacement Devices with Defective Packaging – FDA Safety Communication | Thu, 23 Mar 2023 00:00:00 EDT

Many Exactech knee, ankle, and hip replacement devices were packaged in defective bags and may fail.

Ascend Laboratories LLC. Issues Voluntary Nationwide Recall of Dabigatran Etexilate Capsules, USP 75 mg and 150 mg, Due to the Detection of N-Nitroso-dabigatran (NDAB) Impurity | Wed, 22 Mar 2023 00:00:00 EDT

Parsippany. New Jersey. Ascend Laboratories LLC. is voluntarily recalling Dabigatran Etcxilate Capsules. USP 75 mg and 150 mg to the consumer/user level due to the presence of a nitrosamine. N-nitroso-dabigatran, above the established Acceptable Daily Intake (ADI) level. To date, Ascend Laboratorie ...

UPDATE: Reports of Squamous Cell Carcinoma (SCC) in the Capsule Around Breast Implants - FDA Safety Communication | Wed, 22 Mar 2023 00:00:00 EDT

The FDA updates information on reports of squamous cell carcinoma in the capsule around breast implants.

Datascope/Getinge Recalls Certain Cardiosave Hybrid and Rescue Intra-Aortic Balloon Pumps (IABP) for Risk of Unexpected Shutdown Coiled Cord Connection Failure | Fri, 17 Mar 2023 00:00:00 EDT

The coiled cord on some Cardiosave IABPs may fail and cause an unexpected shutdown, interrupting therapy to the patient with no warning.