Drug updated on 9/13/2023
|Injection (subcutaneous; 50 mg/0.5 mL, 100 mg/mL)
|Tumor necrosis factor (TNF) blocker
| Ongoing and
- Moderately to severely active rheumatoid arthritis (RA) in combination with methotrexate.
- Active psoriatic arthritis (PsA) alone, or in combination with methotrexate.
- Active ankylosing spondylitis (AS).
- Moderate to severe ulcerative colitis (UC) with an inadequate response or intolerant to prior treatment or requiring continuous steroid therapy: inducing and maintaining clinical response, improving endoscopic appearance of the mucosa during induction, inducing clinical remission, and achieving and sustaining clinical remission in induction responders.
Product Monograph / Prescribing Information
|Simponi (golimumab) Prescribing Information.
|Janssen Biotech, Inc. Horsham, PA
Systematic Reviews / Meta-Analyses
|Efficacy and safety of nail psoriasis targeted therapies: a systematic review.
|American Journal of Clinical dermatology
|The efficacy of golimumab against non-infectious uveitis : a prisma-compliant systematic review and meta-analysis.
|Ocular Immunology and Inflammation
|The risk of adverse effects of TNF-α inhibitors in patients with rheumatoid arthritis: a network meta-analysis.
|Frontiers in Immunology
|Comparative efficacy of advanced treatments in biologic-naïve or biologic-experienced patients with ulcerative colitis: a systematic review and network meta-analysis.
|International Journal of Clinical Pharmacology
|Systematic review and network meta-analysis: effect of biologics on radiographic progression in rheumatoid arthritis.
|Journal of Comparative Effectiveness Research
Clinical Practice Guidelines
|Use of biologics and small molecule drugs for the management of moderate to severe ulcerative colitis: IG-IBD clinical guidelines based on the GRADE methodology.
|Digestive and Liver Disease
|2021 American College of Rheumatology guideline for the treatment of rheumatoid arthritis.
|Arthritis and Rheumatology
|ECCO guidelines on therapeutics in ulcerative colitis: medical treatment.
|Journal of Crohn’s and Colitis
|AGA clinical practice guidelines on the management of moderate to severe ulcerative colitis.
|ACG clinical guideline: ulcerative colitis in adults.
|The American Journal of Gastroenterology