ABOUT

DRUGDOCS® provides health professionals with current, evidence-based information on the drugs they prescribe. This information has been collected using an independent, comprehensive and non-biased literature search strategy. Documents included in the DRUGDOCS® database are in no way influenced by third party sponsorship.

Literature Search Strategy

Currently, only drugs approved by the FDA in the past 5 years are included in the DRUGDOCS® database. We are working to have all brand name drugs available in the near future.

Drugs on the DRUDOCS® database were updated every 4 to 6 months using the following search strategy.

For each drug, a literature search was conducted on a number of electronic bibliographic databases (e.g., DARE, HTA, MEDLINE) for English-language health technology assessments, systematic reviews, and meta-analyses. When no health technology assessment, systematic review or meta-analysis was identified, we searched MEDLINE for English-language randomized controlled trials. The National Guideline Clearinghouseâ„¢ and MEDLINE were searched for English-language evidence-based clinical practice guidelines.

STUDY SELECTION CRITERIA:

A Health Technology Assessment was included if it:

  • Included the drug of interest
  • Evaluated the drug for an FDA approved indication
  • Was published within the past 5 years, or within the past 10 years if a Health Technology Assessment, Systematic Review, Meta-Analysis, or RCT published within the past 5 years could not be identified

A Systematic Review or Meta-Analysis was included if it:

  • Included the drug of interest
  • Evaluated the drug for an FDA approved indication
  • Was published within the past 5 years, or within the past 10 years if a Health Technology Assessment, Systematic Review, Meta-Analysis, or RCT published within the past 5 years could not be identified

A Randomised Controlled Trial was included if it:

  • Included the drug of interest
  • Evaluated the drug for an FDA approved indication
  • A Health Technology Assessment, Systematic Review, or Meta-Analysis published within the past 5 years could not be identified
  • Was published within the past 5 years, or within the past 10 years if a Health Technology Assessment, Systematic Review, or Meta-Analysis published within the past 10 years could not be identified

A Clinical Practice Guideline was included if it:

  • Included the drug of interest
  • Evaluated the drug for an FDA approved indication
  • Was published within the past 5 years, or within the past 10 years if a Clinical Practice Guideline published within the past 5 years could not be identified
  • It consisted of evidence-based recommendations, based primarily on the highest level of clinical study evidence available