Perfluorohexyloctane

(Miebo®)

Miebo®

Drug updated on 12/11/2024

Dosage FormOphthalmic solution (topical; 100%)
Drug ClassSemifluorinated alkanes
Ongoing and
Completed Studies
ClinicalTrials.gov

Indication

  • Indicated for treatment of the signs and symptoms of dry eye disease.

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Summary
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  • This summary is based on the review of two systematic review(s)/meta-analysis(es). [1-2]
  • The safety profile of perfluorohexyloctane was noted as effective and safe, though specific details on adverse events were not provided.
  • Ocular treatment-emergent adverse events (TEAES) were fewer in the perfluorohexyloctane group compared to controls the mean difference (MD) was -0.66 ± 1.7, suggesting good tolerability of the drug.
  • The safety profile was mentioned as safe, though specific details regarding adverse events were not provided.
  • Perfluorohexyloctane was associated with fewer ocular treatment-emergent adverse events (MD = -0.66 ± 1.7) compared to control, indicating satisfactory tolerability.
  • The studies focused on patients with Meibomian Gland Dysfunction (MGD) and evaporative dry eye disease (DED). There were no specific subgroup analyses or further population-specific findings provided.