Radium Ra 223 dichloride

(Xofigo®)

Xofigo®

Drug updated on 12/11/2024

Dosage FormInjection (intravenous; 1,100 kBq/mL [30 microcurie/mL])
Drug ClassAlpha particle-emitting radioactive therapeutic agents
Ongoing and
Completed Studies
ClinicalTrials.gov

Indication

  • Indicated for the treatment of patients with castration-resistant prostate cancer, symptomatic bone metastases and no known visceral metastatic disease.

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Summary
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  • This summary is based on the review of one systematic review/meta-analysis. [1]
  • The study notes the potential benefits of radium-223 (Xofigo) in cancer therapy but lacks specific effectiveness outcomes, such as response rates, survival rates, or symptom relief metrics.
  • No comparative effectiveness information is available in the study, as it does not include other drugs for relative assessment.
  • Effectiveness differences among population types or subgroups are not addressed in the study.
  • There is no safety information available in the reviewed studies.

Product Monograph / Prescribing Information

Document TitleYearSource
Xofigo (radium Ra 223 dichloride) Prescribing Information.2019Bayer HealthCare Pharmaceuticals Inc., Whippany, NJ

Systematic Reviews / Meta-Analyses

Document TitleYearSource
Where Do We See Alpha Emitters in Clinical Practice? A Radiation Oncology Perspective2019Journal of Medical Imaging and Radiation Sciences