1 results for: severe aplastic anemia

• Indicated for the treatment of thrombocytopenia in adult and pediatric patients 1 year and older with persistent or chronic immune thrombocytopenia (ITP) who have had an insufficient response to corticosteroids, immunoglobulins, or splenectomy
• PROMACTA should be used only in patients with ITP whose degree of thrombocytopenia and clinical condition increase the risk for bleeding
• Indicated for the treatment of thrombocytopenia in patients with chronic hepatitis C to allow the initiation and maintenance of interferon-based therapy
• PROMACTA should be used only in patients with chronic hepatitis C whose degree of thrombocytopenia prevents the initiation of interferon-based therapy or limits the ability to maintain interferon-based therapy
• Indicated in combination with standard immunosuppressive therapy for the first-line treatment of adult and pediatric patients 2 years and older with severe aplastic anemia
• Indicated for the treatment of patients with severe aplastic anemia who have had an insufficient response to immunosuppressive therapy.

Document title: Efficacy and safety of immunosuppressive therapy combined with eltrombopag for severe aplastic anemia: a systematic review and meta-analysis Document link: https://pmc.ncbi.nlm.nih.gov/articles/PMC10993616/pdf/13643_2024_Article_2515.pdf Document source: Systematic Reviews Document type: Systematic Reviews / Meta-Analyses Document year: 2024

Document title: Safety and efficacy of eltrombopag in patients with aplastic anemia: a systematic review and meta-analysis of randomized controlled trials Document link: https://www.tandfonline.com/doi/epdf/10.1080/16078454.2024.2335419?needAccess=true Document source: Hematology (Amsterdam, Netherlands) Document type: Systematic Reviews / Meta-Analyses Document year: 2024

Document title: Thrombopoietin receptor agonists use and risk of thrombotic events in patients with immune thrombocytopenic purpura: A systematic review and meta‑analysis of randomized controlled trials Document link: https://pmc.ncbi.nlm.nih.gov/articles/PMC10865300/pdf/br-20-03-01732.pdf Document source: Biomedical Reports Document type: Systematic Reviews / Meta-Analyses Document year: 2024

Document title: A Systematic Review and Meta-Analysis of Eltrombopag Efficacy Combined With Immunosuppressive Drugs in Treatment of Severe Aplastic Anemia Document link: https://pmc.ncbi.nlm.nih.gov/articles/PMC11365712/pdf/cureus-0016-00000065970.pdf Document source: Cureus Document type: Systematic Reviews / Meta-Analyses Document year: 2024

Document title: Guidelines for the diagnosis and management of adult aplastic anaemia: a British Society for Haematology guideline Document link: https://onlinelibrary.wiley.com/doi/epdf/10.1111/bjh.19236 Document source: British Journal of Haematology Document type: Clinical Practice Guidelines Document year: 2024

Document title: Promacta (eltrombopag) Prescribing Information. Document link: https://www.novartis.com/us-en/sites/novartis_us/files/promacta.pdf Document source: Novartis Pharmaceuticals Corporation, East Hanover, NJ Document type: Product Monograph / Prescribing Information Document year: 2023

Document title: European Delphi panel to build consensus on tapering and discontinuing thrombopoietin receptor agonists in immune thrombocytopenia Document link: https://www.tandfonline.com/doi/epdf/10.1080/09537104.2023.2170999?needAccess=true Document source: Platelets Document type: Clinical Practice Guidelines Document year: 2023

Document title: Efficacy and Incidence of Treatment-Related Adverse Events of Thrombopoietin Receptor Agonists in Adults with Immune Thrombocytopenia: A Systematic Review and Network Meta-Analysis of Randomized Controlled Study Document link: https://karger.com/aha/article-pdf/146/3/173/3949418/000528642.pdf Document source: Acta Haematologica Document type: Systematic Reviews / Meta-Analyses Document year: 2023

Document title: Efficacy and safety of thrombopoietin receptor agonists in children and adults with persistent and chronic immune thrombocytopenia: a meta-analysis Document link: https://www.tandfonline.com/doi/epdf/10.1080/14656566.2023.2198089?needAccess=true Document source: Expert Opinion on Pharmacotherapy Document type: Systematic Reviews / Meta-Analyses Document year: 2023

Document title: The efficacy and the safety of eltrombopag in pediatric patients with severe aplastic anemia: a systematic review Document link: https://pmc.ncbi.nlm.nih.gov/articles/PMC10166202/pdf/fped-11-1149718.pdf Document source: Frontiers in Pediatrics Document type: Systematic Reviews / Meta-Analyses Document year: 2023

Document title: Risk of thrombotic events in immune thrombocytopenia patients treated with thrombopoietic agents: a systematic review and meta-analysis Document link: https://pmc.ncbi.nlm.nih.gov/articles/PMC10290365/pdf/12959_2023_Article_509.pdf Document source: Thrombosis Journal Document type: Systematic Reviews / Meta-Analyses Document year: 2023

Document title: Eltrombopag for Adults and Children with Immune-Refractory Thrombocytopenic Purpura: A Systematic Review Document link: https://pmc.ncbi.nlm.nih.gov/articles/PMC10299452/pdf/jcm-12-03872.pdf Document source: Journal of Clinical Medicine Document type: Systematic Reviews / Meta-Analyses Document year: 2023

Document title: Thrombopoietin receptor agonists and rituximab for treatment of pediatric immune thrombocytopenia: A systematic review and meta-analysis of prospective clinical trials Document link: https://onlinelibrary.wiley.com/doi/epdf/10.1002/pbc.29447 Document source: Pediatric Blood & Cancer Document type: Systematic Reviews / Meta-Analyses Document year: 2022

Document title: EHA guidelines on management of antithrombotic treatments in thrombocytopenic patients with cancer Document link: https://pmc.ncbi.nlm.nih.gov/articles/PMC9281983/pdf/hs9-6-e750.pdf Document source: Hemasphere Document type: Clinical Practice Guidelines Document year: 2022

Document title: Efficacy and Safety of Avatrombopag in Patients with Chronic Immune Thrombocytopenia: A Systematic Literature Review and Network Meta-Analysis Document link: https://pmc.ncbi.nlm.nih.gov/articles/PMC8189936/pdf/12325_2021_Article_1752.pdf Document source: Advances in therapy Document type: Systematic Reviews / Meta-Analyses Document year: 2021

Document title: Eltrombopag Effectiveness and Tolerability in Chronic Immune Thrombocytopenia: A Meta-Analysis Document link: https://pmc.ncbi.nlm.nih.gov/articles/PMC8060759/pdf/10.1177_10760296211005555.pdf Document source: Clinical and Applied Thrombosis/Hemostasis Document type: Systematic Reviews / Meta-Analyses Document year: 2021

Document title: Treatment efficacy for adult persistent immune thrombocytopenia: a systematic review and network meta-analysis Document link: https://pmc.ncbi.nlm.nih.gov/articles/PMC7003949/pdf/BJH-188-450.pdf Document source: British Journal of Haematology Document type: Systematic Reviews / Meta-Analyses Document year: 2020

Document title: Therapeutic options for adult patients with previously treated immune thrombocytopenia - a systematic review and network meta-analysis Document link: https://www.tandfonline.com/doi/epdf/10.1080/16078454.2019.1568659?needAccess=true Document source: Hematology (Amsterdam, Netherlands) Document type: Systematic Reviews / Meta-Analyses Document year: 2019