Zejula

Chemical Nameniraparib
Dosage FormCapsule (oral; 100 mg)
Drug ClassPoly (ADP-ribose) polymerase (PARP) inhibitors
SystemMultiple
CompanyGlaxoSmithKline
Approval Year2017

Indication

  • For the maintenance treatment of adult patients with advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete or partial response to first-line platinum-based chemotherapy.
  • For the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete or partial response to platinum-based chemotherapy.
  • For the treatment of adult patients with advanced ovarian, fallopian tube, or primary peritoneal cancer who have been treated with 3 or more prior chemotherapy regimens and whose cancer is associated with homologous recombination deficiency (HRD) positive status defined by either a deleterious or suspected deleterious BRCA mutation, or genomic instability and who have progressed more than 6 months after response to the last platinum-based chemotherapy.
Last updated on 10/19/2022

More on this drug: Clinical Trials

Document TitleYearSource
Zejula (Niraparib) Prescribing Information.2022GlaxoSmithKline, Research Triangle Park, NC