Chemical Nameglucarpidase
Dosage FormInjection (intravenous; 1000 units/vial)
Drug ClassEnzymes
CompanyBTG International
Approval Year2012


  • For the treatment of toxic plasma methotrexate concentrations (>1 micromole per liter) in patients with delayed methotrexate clearance due to impaired renal function
Last updated on 4/19/2022

More on this drug: Clinical Trials

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Document TitleYearSource
Voraxaze (glucarpidase) Prescribing Information.2012BTG International Inc. Brentwood, TN
Document TitleYearSource
Assessment report: Voraxaze. 2021EMA
Document TitleYearSource
Extracorporeal treatment for methotrexate poisoning systematic review and recommendations from the EXTRIP workgroup. 2022Clinical Journal of the American Society of Nephrology