Trintellix

Chemical Namevortioxetine
Dosage FormTablet (oral; 5mg, 10mg, 15mg, and 20mg)
Drug ClassAntidepressants
SystemNervous
CompanyLundbeck
Approval Year2013

Indication

  • For the treatment of major depressive disorder (MDD).
Last updated on 4/27/2021

More on this drug: Clinical Trials

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Document TitleYearSource
Trintellix (vortioxetine) Prescribing Information2013Takeda Pharmaceuticals America, Deerfield, IL
Document TitleYearSource
Comparative efficacy of pharmacological treatments on measures of self-rated functional outcomes using the Sheehan Disability Scale in patients with major depressive disorder: a systematic review and network meta-analysis.2021CNS Spectrums
Gastrointestinal side effects associated with antidepressant treatments in patients with major depressive disorder: A systematic review and meta-analysis.2021Progress in Neuro-Psychopharmacology and Biological Psychiatry
Systematic review of gender bias in vortioxetine clinical trials.2020Progress in Neuro-Psychopharmacology and Biological Psychiatry
Efficacy and tolerability of pharmacological and non-pharmacological interventions in older patients with major depressive disorder: A systematic review, pairwise and network meta-analysis.2019European Neuropsychopharmacology
Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis.2018The Lancet
Efficacy and safety of levomilnacipran, vilazodone and vortioxetine compared with other second-generation antidepressants for major depressive disorder in adults: A systematic review and network meta-analysis.2018Journal of Affective Disorders
Vortioxetine for depression in adult.2017Cochrane Database of Systematic Reviews
Meta-analysis: Risk of hyperhidrosis with second-generation antidepressants.2017Depression and Anxiety
Systematic review of randomized controlled trials of candidate treatments for cognitive impairment in depression and methodological challenges in the field.2016European Neuropsychopharmacology
Vortioxetine versus duloxetine in the treatment of patients with major depressive disorder: A meta-analysis of randomized controlled trials.2016Clinical Drug Investigation