Drug updated on 11/15/2023

Dosage FormInjection (subcutaneous; 150mg/mL)
Drug ClassInterleukin-13 antagonists
Ongoing and
Completed Studies


  • For the treatment of moderate-to-severe atopic dermatitis in adult patients whose disease is not adequately controlled with topical prescription therapies or when those therapies are not advisable.

Product Monograph / Prescribing Information

Document TitleYearSource
Adbry (tralokinumab-ldrm) Prescribing Information.2022LEO Pharma Inc., Madison, NJ

Systematic Reviews / Meta-Analyses

Document TitleYearSource
Comparing binary efficacy outcomes for systemic immunomodulatory treatments for atopic dermatitis in a living systematic review and network meta-analysis. 2023British Journal of Dermatology
Systemic treatments for atopic dermatitis (eczema): systematic review and network meta-analysis of randomized trials. 2023Journal of Allergy and Clinical Immunology
Efficacy and safety of tralokinumab in the treatment of atopic dermatitis: A systematic review and meta-analysis of randomized controlled trials. 2023Medicine
Clinical and pharmacoeconomic combined report: tralokinumab (Adtralza). 2022CADTH
Assessment report: Adtralza.2022EMA
The efficacy and safety of IL-13 inhibitors in atopic dermatitis: a systematic review and meta-analysis.2022Frontiers in Immunology
Systemic immunomodulatory treatments for atopic dermatitis: update of a living systematic review and network meta-analysis.2022JAMA Dermatology
Comparative Efficacy and Safety of Monoclonal Antibodies and Janus Kinase Inhibitors in Moderate-to-severe Atopic Dermatitis: A Systematic Review and Meta-analysis. 2022Acta Dermato-venereologica
JAK inhibitors and monoclonal antibodies for the treatment of atopic dermatitis: effectiveness and value.2021ICER
Comparative efficacy and safety of systemic therapies used in moderate-to-severe atopic dermatitis: a systematic literature review and network meta-analysis.2021Journal of The European Academy of Dermatology and Venereology
Biological Therapies for Atopic Dermatitis: A Systematic Review.2021Dermatology
Systemic treatments for eczema: a network meta-analysis.2020Cochrane Database of Systematic Reviews
Effect of monoclonal antibody drug therapy on mucosal biomarkers in airway disease: a systematic review.2020Clinical & Experimental Allergy
Are biologics efficacious in atopic dermatitis? A systematic review and meta-analysis.2018American Journal of Clinical Dermatology