Drug updated on 12/11/2024
| Dosage Form | Ophthalmic solution (topical; 100%) | 
| Drug Class | Semifluorinated alkanes | 
|  Ongoing and  Completed Studies  | ClinicalTrials.gov | 
Indication
- Indicated for treatment of the signs and symptoms of dry eye disease.
 
Latest News

Summary
- This summary is based on the review of two systematic review(s)/meta-analysis(es). [1-2]
 - The safety profile of perfluorohexyloctane was noted as effective and safe, though specific details on adverse events were not provided.
 - Ocular treatment-emergent adverse events (TEAES) were fewer in the perfluorohexyloctane group compared to controls the mean difference (MD) was -0.66 ± 1.7, suggesting good tolerability of the drug.
 - The safety profile was mentioned as safe, though specific details regarding adverse events were not provided.
 - Perfluorohexyloctane was associated with fewer ocular treatment-emergent adverse events (MD = -0.66 ± 1.7) compared to control, indicating satisfactory tolerability.
 - The studies focused on patients with Meibomian Gland Dysfunction (MGD) and evaporative dry eye disease (DED). There were no specific subgroup analyses or further population-specific findings provided.
 
Product Monograph / Prescribing Information
| Document Title | Year | Source | 
|---|---|---|
| Miebo (perfluorohexyloctane) Prescribing Information. | 2023 | Bausch & Lomb Americas Inc., Bridgewater, NJ | 

