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Movantik

Chemical Namenaloxegol
Dosage FormTablet (oral; 12.5 mg, 25 mg)
Drug ClassOpioid antagonists
SystemDigestive
CompanyRedHill Biopharma
Approval Year2014

Indication

  • For the treatment of opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain, including patients with chronic pain related to prior cancer or its treatment who do not require frequent (e.g., weekly) opioid dosage escalation.
Last updated on 11/14/2022

More on this drug: Clinical Trials

Document TitleYearSource
Movantik (naloxegol) Prescribing Information.2020RedHill Biopharma Inc., Raleigh, NC
Document TitleYearSource
Australian public assessment report for naloxegol oxalate.2016Australian Government: Department of Health
Naloxegol for treating opioid-induced constipation. 2015NICE
Assessment report: Movantig.2014EMA
Document TitleYearSource
Management of opioid-induced and non–opioid-related constipation in patients with cancer: Systematic review and meta-analysis. 2020Oncology Nursing Forum
Systematic review with meta-analysis: efficacy and safety of treatments for opioid-induced constipation.2020Alimentary Pharmacology and Therapeutics
Drugs for treating opioid-induced constipation: A mixed treatment comparison network meta-analysis of randomized controlled clinical trials.2018Journal of Pain and Symptom Management
Efficacy of treatments for opioid-induced constipation: systematic review and meta-analysis.2018Clinical Gastroenterology and Hepatology
The efficacy of peripheral opioid antagonists in opioid-induced constipation and postoperative ileus: A systematic review of the literature.2017Regional Anesthesia and Pain Medicine
Document TitleYearSource
American Gastroenterological Association Institute guideline on the medical management of opioid-induced constipation.2019Gastroenterology
Diagnosis, assessment and management of constipation in advanced cancer: ESMO clinical practice guidelines.2018Annals of Oncology