Drug updated on 11/14/2023

Dosage FormCapsule (oral: 25 mg)
Drug ClassKinase inhibitors
Ongoing and
Completed Studies


  • For the treatment of adult patients with newly diagnosed acute myeloid leukemia (AML) that is FLT3 mutation positive as detected by an FDA-approved test, in combination with standard cytarabine and daunorubicin induction and cytarabine consolidation.
  • For the treatment of adult patients with aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematological neoplasm (SM-AHN), or mast cell leukemia (MCL).

Product Monograph / Prescribing Information

Document TitleYearSource
Rydapt (Midostaurin) Prescribing Information.2021Novartis Pharmaceuticals Corporation, East Hanover, NJ

Systematic Reviews / Meta-Analyses

Clinical Practice Guidelines