Lumacaftor/ivacaftor

(Orkambi)

Lumacaftor/ivacaftor

Drug updated on 6/5/2023

Dosage FormTablet (oral; lumacaftor/ivacaftor: 100/125 mg, 200/125 mg); Granules (oral; lumacaftor/ivacaftor: 100/125 mg, 150/188 mg)
Drug ClassCystic fibrosis transmembrane conductance regulator (CFTR) potentiators
Ongoing and Completed StudiesClinicalTrials.gov

Indication

  • For the treatment of cystic fibrosis (CF) in patients age 2 years and older who are homozygous for the F508del mutation in the CFTR gene.