Drug updated on 9/4/2024
Dosage Form | Capsule (oral; 30 mg) |
Drug Class | Iron replacement products |
Ongoing and Completed Studies | ClinicalTrials.gov |
Indication
- Indicated for the treatment of iron deficiency in adults.
Latest News
Summary
- Accrufer (ferric maltol) is indicated for the treatment of iron deficiency in adults.
- This summary is based on the review of one systematic review(s)/meta-analysis(es). [1]
- Intravenous ferric carboxymaltose is likely superior to intravenous iron sucrose in increasing hemoglobin in patients with iron deficiency anemia, with a responder rate of 150/244 compared to 118/239 (RR 1.25, 95% CI 1.06 to 1.46, NNTB = 9).
- Oral ferric maltol is likely more effective than placebo in increasing hemoglobin, with responders being 36/64 for ferric maltol versus 0/64 for placebo (RR 73.00, 95% CI 4.58 to 1164.36).
- Intravenous iron preparations generally result in more hemoglobin responders compared to oral preparations, with responder rates of 368/554 versus 205/373 (RR 1.17, 95% CI 1.05 to 1.31, NNTB = 11).
- Withdrawals due to adverse events may be higher in oral iron preparations compared to intravenous iron preparations (15/554 vs. 31/373, RR 0.39, 95% CI 0.20 to 0.74).
- No significant differences in serious adverse events were observed among the different treatment arms, but the certainty of the evidence was very low due to the low number of reported events.
- There is no population types or subgroups information available in the reviewed studies.
Product Monograph / Prescribing Information
Document Title | Year | Source |
---|---|---|
Accrufer (ferric maltol) Prescribing Information. | 2022 | Shield Therapeutics Inc, North Austin, TX |
Systematic Reviews / Meta-Analyses
Document Title | Year | Source |
---|---|---|
Interventions for treating iron deficiency anaemia in inflammatory bowel disease. | 2021 | The Cochrane Database of Systematic Reviews |
Clinical Practice Guidelines
Document Title | Year | Source |
---|---|---|
British Society of Gastroenterology guidelines for the management of iron deficiency anaemia in adults. | 2021 | Gut |