Drug updated on 7/25/2024
Dosage Form | Capsule (oral; 30 mg) |
Drug Class | Iron replacement products |
Ongoing and Completed Studies | ClinicalTrials.gov |
Indication
- Indicated for the treatment of iron deficiency in adults.
Latest News
Summary
- Ferric maltol (Accrufer) is indicated for the treatment of iron deficiency in adults.
- The information was derived from two systematic reviews/meta-analyses documents.
- In a study involving adults and children with inflammatory bowel disease (IBD), oral ferric maltol showed low-certainty evidence of being superior to placebo in resolving iron deficiency anemia (IDA).
- Compared to intravenous preparations like IV ferric carboxymaltose, which had moderate-certainty evidence suggesting superiority over IV iron sucrose, oral ferric maltol's effectiveness was less favorable but still notable against placebo.
- Safety profiles indicate that while adverse events were inconsistently reported across studies, there is low-certainty evidence showing little difference in adverse events between oral ferric maltol and placebo.
- Population considerations highlight varying efficacy and safety among different age groups and stages of IBD; more research is needed specifically targeting fatigue management within these subpopulations.
Product Monograph / Prescribing Information
Document Title | Year | Source |
---|---|---|
Accrufer (ferric maltol) Prescribing Information. | 2022 | Shield Therapeutics Inc, North Austin, TX |
Systematic Reviews / Meta-Analyses
Document Title | Year | Source |
---|---|---|
Interventions for treating iron deficiency anaemia in inflammatory bowel disease. | 2021 | The Cochrane Database of Systematic Reviews |
Interventions for fatigue in inflammatory bowel disease. | 2020 | The Cochrane Database of Systematic Reviews |
Clinical Practice Guidelines
Document Title | Year | Source |
---|---|---|
British Society of Gastroenterology guidelines for the management of iron deficiency anaemia in adults. | 2021 | Gut |