To treat metastatic Merkel cell carcinoma in patients ≥ 12 years of age.
To treat locally advanced or metastatic urothelial carcinoma in patients with disease progression during or following platinum-containing chemotherapy and who have had disease progression within 12 months of neoadjuvant or adjuvant treatment with platinum-containing chemotherapy.
To treat advanced renal cell carcinoma as a first line treatment in conjunction with axitinib.