Spikevax (Moderna COVID-19 Vaccine)

(COVID-19 Vaccine, mRNA)

Spikevax (Moderna COVID-19 Vaccine)

Drug updated on 11/15/2023

Dosage FormInjection (intramuscular; 0.5mL)
Drug ClassImmunological Agents
Ongoing and Completed StudiesClinicalTrials.gov


  • Indicated for active immunization to prevent coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in individuals 18 years of age and older.

Product Monograph / Prescribing Information

Document TitleYearSource
Spikevax (COVID-19 Vaccine, mRNA) Prescribing Information.2022Moderna US, Inc., Cambridge, MA

Systematic Reviews / Meta-Analyses

Document TitleYearSource
Risks of cardiac arrhythmia associated with covid-19 vaccination: a systematic review and meta-analysis.2023Vaccines
The efficacy and effectiveness of COVID-19 vaccines around the world: a mini-review and meta-analysis.2023Annals of Clinical Microbiology and Antimicrobials
Adverse events following COVID-19 mRNA vaccines: a systematic review of cardiovascular complication, thrombosis, and thrombocytopenia.2023Immunity, Inflammation and Disease
Vaccine efficacy against SARS-CoV-2 for Pfizer BioNTech, Moderna, and AstraZeneca vaccines: a systematic review. 2023Frontiers in Public Health
Safety and effectiveness of vaccines against COVID-19 in children aged 5-11 years: a systematic review and meta-analysis. 2023The Lancet. Child & Adolescent Health
Localised swelling at sites of dermal filler injections following administration of Covid-19 vaccines: a systematic review. 2023Singapore medical journal
Efficacy and safety of COVID-19 vaccines.2022Cochrane Database of Systematic Reviews
Lymphadenopathy post-COVID-19 vaccination with increased FDG uptake may be falsely attributed to oncological disorders: a systematic review.2022Journal of Medical Virology
COVID-19 vaccine induced myocarditis in young males: A systematic review.2022European Journal of Clinical Investigation
mRNA Covid-19 vaccines in pregnancy: a systematic review.2021PLoS One
Effectiveness of COVID-19 vaccines against Delta (B.1.617.2) variant: a systematic review and meta-analysis of clinical studies.2021Vaccines
Evaluation of the safety profile of COVID-19 vaccines: a rapid review.2021BMC Medicine
Anaphylactic and nonanaphylactic reactions to SARS-CoV-2 vaccines: a systematic review and meta-analysis.2021Allergy, Asthma & Clinical Immunology