Air polymer-type A

(ExEm Foam®)

Exem Foam®

Drug updated on 9/5/2024

Dosage Formfoam (intrauterine; single dose kit: one syringe with 5 mL clear Gel [polymer type A–hydoxyethyl cellulose, glycerin and purified water], one syringe with 5 mL Sterile Purified Water and one Combifix® Adaptor [coupling device])
Drug ClassUltrasound contrast agents
Ongoing and
Completed Studies
ClinicalTrials.gov

Indication

  • Indicated for sonohysterosalpingography to assess fallopian tube patency in women with known or suspected infertility.

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Summary
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  • Exem Foam (air polymer-type a) is indicated for sonohysterosalpingography to assess fallopian tube patency in women with known or suspected infertility.
  • This summary is based on the review of one systematic review(s)/meta-analysis(es). 3. [1]
  • D-HyCoSy: Demonstrated a sensitivity of 86% (95% CI: 80%-91%) and a specificity of 94% (95% CI: 90%-96%) in assessing tubal occlusion in women with infertility. 4.
  • D/4D-HyCoSy: Showed a sensitivity of 95% (95% CI: 89%-98%) and a specificity of 89% (95% CI: 82%-94%) for the same condition.
  • Comparison: 3D/4D-HyCoSy had higher sensitivity (95% vs. 86%), while 2D-HyCoSy had higher specificity (94% vs. 89%). No statistically significant differences were found between the methods (p = 0.13).
  • There is no safety information available in the reviewed studies.
  • There is no population types or subgroups information available in the reviewed studies.